Targeted Human Methylome Sequencing

Explore the Epigenetic Landscape with Nucleome Informatics’ Twist Human Methylome Panel

Welcome to Nucleome Informatics’ Methylome Sequencing Service, where we bring you the transformative Twist Human Methylome Panel – an exceptional tool designed to unravel the complexities of DNA methylation. With precision targeting of 3.98 million CpG sites across 123 megabases of genomic content, this panel homes in on biologically relevant methylation markers, opening up a world of possibilities for investigators across diverse applications.

Comprehensive Coverage for In-Depth Analysis

Nucleome Informatics’ Twist Human Methylome Panel boasts expansive content, making it the perfect choice for investigating the methylation fraction in a wide range of areas, including cancer metastasis, human development, and functional genomics. No matter your research focus, this panel provides the depth and breadth of information you need to make groundbreaking discoveries.

Seamless Integration with Twist Methylation Detection System

Our panel is fully optimized and rigorously validated for use with the Twist methylation detection system, offering you a complete end-to-end workflow with industry-leading performance. Experience enhanced capture efficiency, elevating the sensitivity of detection across the entire epigenome footprint while simultaneously reducing sequencing costs. Say goodbye to unnecessary complexities and focus on what truly matters – advancing your research.

Empowering Cohort Studies and Discovery

Nucleome Informatics’ Twist Human Methylome Panel is a game-changer for screening cohort samples and identifying differentially methylated regions. With its robust performance, it accelerates your research and delivers valuable insights into the dynamic world of DNA methylation. Unlock the hidden potential of epigenetics and pave the way for novel discoveries that can shape the future of medicine and beyond.

Key Benefits of Nucleome Informatics’ Twist Human Methylome Panel

• Design and Workflow Efficiency: Experience a seamless and efficient research journey from start to finish.
• Optimized Performance: Achieve unmatched performance with our integrated end-to-end workflow.
• Increased Library Complexity: Elevate your sequencing data quality with enhanced library complexity.
• Flexibility in Content: Customize your research with the option to add spike-in content for tailored analysis.
• Broader Coverage: Surpass the limitations of average microarrays with ~4x more coverage of all CpG sites.
• More Coverage of CpG Islands: Get detailed insights with enhanced coverage of CpG island bases.
• Updated Reference Databases: Rely on the latest information for your research, backed by updated reference databases.
• Advantage over Microarrays: Enjoy higher calls at differentially methylated regions and increased coverage of adjacent CpG sites upstream and downstream.

Join the Epigenetic Revolution with Nucleome Informatics

At Nucleome Informatics, we are dedicated to empowering researchers like you with cutting-edge solutions. Explore the intricate world of epigenetics with the Twist Human Methylome Panel and uncover the hidden language of DNA methylation. Contact us today to learn more about our services and how we can propel your research forward. Together, let’s make history in the realm of epigenetics.